PROTOCOLOS CLÍNICOS E DIRETRIZES TERAPÊUTICAS

Uveítes Posteriores Não Infecciosas Uveítes Posteriores Não Infecciosas • reavaliações clínicas com o médico assistente devem ser definidas de acordo com a gravidade da doença, a resposta ao tratamento, os efeitos adversos e as complicações oculares. 14 T ermo de Esclarecimento e Responsabilidade – TER É obrigatória a informação ao paciente ou a seu responsável legal dos potenciais riscos, benefícios e efeitos adversos relacionados ao uso dos medicamentos preconizados neste protocolo. O TER é obrigatório ao se prescrever medicamento do Componente Especializado da Assistência Farmacêutica. 15 R eferências Bibliográficas 1. Wakefield D, Chang JH. Epidemiology of uveitis. Int Ophthalmol Clin. 2005;45(2):1-13. 2. Kim EC, Foster CS. Immunomodulatory therapy for the treatment of ocular inflammatory disease: evidence- based medicine recommendations for use. Int Ophthalmol Clin. 2006;46(2):141-64. 3. Díaz-Valle D, Méndez R, Arriola P, Cuiña R, Ariño M. [Non-infectious systemic diseases and uveítes]. An Sist Sanit Navar. 2008:31(Suppl 3):97-110. Spanish. 4. Briggs GG, Freeman RK, Yaffe SJ. Drugs in pregnancy and lactation: A reference guide to fetal and neonatal risk. 5th edition. Philadelphia: Linppincott Williams &Wilkins; 1998. 5. Bermas BL. Use of immunosuppressive drugs in pregnancy and lactation [Internet]. Waltham (MA): UpToDate; 2009 [cited 2010 May 26]. Available from: http://www.uptodate.com/patients/content/topic.do?topicKey=~ UJr 7b8x6Y856O&selectedTitle=4~150. 6. Jabs DA, Rosenbaum JT, Foster CS, Holland GN, Jaffe GJ, Louie JS, et al. Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am J Ophthalmol. 2000;130(4):492-513. 7. Nussenblatt RB, Palestine AG, Chan CC, Stevens G Jr, Mellow SD, Green SB. Randomized, double-masked study of cyclosporine compared to prednisolone in the treatment of endogenous uveitis. Am J Ophthalmol. 1991;112(2):138-46. 8. Masuda K, Nakajima A, Urayama A, Nakae K, Kogure M, Inaba G. Double-masked trial of cyclosporin versus colchicine and long-term open study of cyclosporin in Behçet’s disease. Lancet. 1989;1(8647):1093-6. 9. Vitale AT, Rodriguez A, Foster CS. Low-dose cyclosporin A therapy in treating chronic, noninfectious uveitis. Ophthalmology. 1996;103(3):365-73. 10. de Vries J, Baarsma GS, Zaal MJ, Boen-Tan TN, Rothova A, Buitenhuis HJ, et al. Cyclosporin in the treatment of severe chronic idiopathic uveitis. Br J Ophthalmol. 1990;74(6):344-9. 11. BenEzra D, Cohen E, Chajek T, Friedman G, Pizanti S, de Courten C, et al. Evaluation of conventional therapy versus cyclosporine A in Behçet’s syndrome. Transplant Proc. 1988:20(3 Suppl 4):136-43. 12. Whitcup SM, Salvo EC Jr, Nussenblatt RB. Combined cyclosporine and corticosteroid therapy for sight- threatening uveitis in Behçet’s disease. Am J Ophthalmol. 1994;118(1):39-45. 13. Jap A, Chee SP. Immunosuppressive therapy for ocular diseases. Curr Opin Ophthalmol. 2008;19(6):535-40. 14. Michel SS, Ekong A, Baltatzis S, Foster CS. Multifocal choroiditis and panuveitis: immunomodulatory therapy. Ophthalmology. 2002;109(2):378-83. 15. Vitale AT, Rodriguez A, Foster CS. Low-dose cyclosporine therapy in the treatment of birdshot retinochoroidopathy. Ophthalmology. 1994;101(5):822-31. 16. Mendes D, Correia M, Barbedo M, Vaio T, Mota M, Gonçalves O, et al. Behçet’s disease: a contemporary review. J Autoimmun. 2009;32(3-4):178-88. Epub 2009 Mar 26. 17. Chan CC, Roberge RG, Whitcup SM, Nussenblatt RB. 32 cases of sympathetic ophthalmia. A retrospective study at the National Eye Institute, Bethesda, Md., from 1982 to 1992. Arch Ophthalmol. 1995;113(5):597-600. 18. Akpek EK, Baltatzis S, Yang J, Foster CS. Long-term immunosuppressive treatment of serpiginous choroiditis. Ocul Immunol Inflamm. 2001;9(3):153-67. 19. Fang W, Yang P. Vogt-koyanagi-harada syndrome. Curr Eye Res. 2008;33(7):517-23. 20. Murphy CC, Greiner K, Plskova J, Duncan L, Frost NA, Forrester JV, et al. Cyclosporine vs tacrolimus therapy for posterior and intermediate uveitis. Arch Ophthalmol. 2005;123(5):634-41. 21. Ozyazgan Y, Yurdakul S, Yazici H, Tüzün B, Isçimen A, Tüzün Y, et al. Low dose cyclosporin A versus pulsed 583

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